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Firstly, transplantation of gut microbiota from human donors with ASD induced core ASD behaviors in mice, whose brains showed alternative splicing of ASD-related genes ( More recently, another dimension was added to this axis given the aberrant immune responses and inflammatory profiles widely reported in ASD ( Given the ability of the microbiota to produce psychoactive chemicals that are hormones or have hormonal qualities and considering the gut microbiota as a unique collective endocrine organ, Obrenovich et al

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