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MTHFR in Inflammation Inflammation is mediated primarily by the nuclear factor kappa-light-chain-enhancer of activated B-cells (NF-B) pathway, which involves several related transcription factors

In the meanwhile, they achieve the uptake of essential nutrients and clearance of exogenous substances via carrier proteins (e.g., glucose transporter, GLUT) and efflux pumps (e.g., P-glycoprotein, P-gP) on the cell membrane, realizing regulation of transmembrane transport processes

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