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Description
Specifically, circulating LPS binds to TLR4 on immune cell surfaces, activating the downstream NF-B signaling pathway and promoting the release of pro-inflammatory cytokines such as tumor necrosis factor-alpha (TNF-), interleukin-6 (IL-6), and interleukin-1 beta (IL-1)

A pilot randomized clinical trial: Oral miltefosine and pentavalent antimonials associated with pentoxifylline for the treatment of American tegumentary leishmaniasis

A: Injections typically offer higher bioavailability

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