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doi: 10.1016/j.cellsig.2007.11.012

This has led to significant interest in studies focused on calorie intake, nutrient consumption, weight gain protocols, and bulking-related research

It was subsequently shown that free glutamine is abundant in certain plants, but relatively little was known about the metabolism of glutamine until the1930s, when it was directly demonstrated that glutamine is a component of proteinS3 and when Hans Krebs first described the capacity for glutamine hydrolysis and glutamine synthesis in mammalian tissues

Cameron et al
