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In NRK-52E cells, urografin induced apoptosis in a time- and dose-dependent manner and activated an ERS response characterized by increased GRP78/GRP94 expression and PERKeIF2 phosphorylation

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This effect typically resolves as the body adjusts to altered metabolic signaling

Ans : Yes, if gallstones are present in both the gallbladder and bile ducts, use K80.6 (Calculus of the gallbladder and bile duct with cholecystitis) or K80.7 (without cholecystitis)