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however, this theory has been called into question as APAP-protein adducts have been detected at 1 hour after APAP treatment, a time that that would precede GSH depletion

PI3K/AKT Pathway and Its Mediators in Thyroid Carcinomas

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Cellular iron uptake, storage, and trafficking The beneficial properties of iron for redox reactions also render iron toxic when in excess, generating reactive oxygen species (ROS) via Fenton reactions [13]
