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Description
Optimized LC-MS/MS parameters for the analysis of eicosanoids are in accordance with previous research ( Inhibition of Cyclooxygenase 1 (COX-1) and Cyclooxygenase 2 (COX-2) in Cell-Free Assays Cyclooxygenase (COXs) can convert AA to PGG 2 , and further reduce PGG 2 to PGH 2
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Aluminum hydroxide (Alum) is used as an adjuvant to enhance immunogenicity, while excipients such as phosphate buffers and sodium chloride help maintain isotonicity
Left, metabolites also identified through comparisons to chemical standards under identical LC-MS/MS conditions in human or mouse
