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however, the involvement of CYP3A5 in acetaminophen oxidation has not been reported and if occurs, it might be due to a big overlap in substrate selectivity between CYP3A enzymes

doi:10.1016/B978-0-444-62627-1.00023-8

Winkler, A

NHS guidance on vitamin B12 says theres not enough evidence to show what the effects may be of taking high doses of vitamin B12 supplements each day, and therefore you should not take more than has been advised by your doctor
