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Because of that, plants developed complexed ROS control system based on enzymes (like glutathione reductase-GR, glutathione S-transferase-GST, glutathione peroxidase-GPX) and scavenging non-enzymatic hydrophilic molecules like ascorbate (AsA) and glutathione (GSH) (Noctor and Foyer, 1998)

Moreover, UPR activation in adipocytes dramatically alters adipokine production patterns, with adiponectin secretion decreased while inflammatory cytokines including IL-6 and resistin are increased (101, 102)

Such stress inducers are currently considered promising anticancer drugs [282]

D., Banerjee, R., Liu, J., Gendelman, H