google scholar glutathione Participation in the Prevention of Cardiovascular Diseases Cellular Compartmentalization, Glutathione Transport and
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R.SilvaM

PMM is internalized via endocytosis and sequestered in vacuoles, where vacuolar ATPase pumps are upregulated to isolate the drug, reducing its efficacy

Hill et al., 2014

Instead, S-8 injury predominantly occurred just above the alveoli in the small airways (bronchiolar area), particularly in club cells
