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The severity of acute radiodermatitis is usually classified in 4 levels according to the fourth version of the unified criteria of the National Cancer Institute7 (Table 3)

STO609 improved the levels of anti-lipid peroxidation proteins, such as GSH, GPX4, and SLC7A11 (Figure 6B, F, G)

Moreover, environmental factors, such as heavy metals, also contribute to excessive ROS

For the GST-pulldown assay using GST-Raf1-RBD (Merk), Kras- and STAND-Y13-259-expressing vectors were co-transfected into 293 T cells using Lipofectamine 2000