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Additionally, we will address aspects initially not considered in detail, such as the role of different families of IgG Fc receptors (FcRs), which may influence interactions among mAbs, the environment, and MM cells

Traditional treatments like NSAIDs and corticosteroids provide temporary relief but come with significant drawbacks

Bone tissue undergoes continuous remodeling, allowing for the restoration of structure and function after injury ( Autologous bone transplantation is currently considered the gold standard for bone defect restoration, distinguished by its osteogenesis, osteoconduction and osteoinduction properties

From a pharmacological perspective, tirzepatide acts primarily through GIP and GLP-1 receptor pathways to modulate insulin secretion, glucagon suppression, and appetite regulation