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In the plasma, IGFBP-3 is bound to a protein called acid labile subunit (ALS), which stabilizes the IGFBP3-IGF-I complex, prolonging its half-life to approximately 16 hours (71)
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doi:10.1046/j.1524-475X.1994.20406.x Leyden J, Stephens T, Finkey MB, Barkovic S, Schweiger D
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