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The insulin-like growth factor 1 (IGF-1) is a hormone widely expressed throughout the body that plays a crucial role in promoting anabolic processes

Macrophages have immunological function in bacterial, viral and parasitic infections, and they also function in inflammatory and hemostatic processes [90,91]

Of a particular interest, poly(lactide-co-glycolide) (PLGA) is a biocompatible and biodegradable polyester, which is used in several FDA-approved products in the form of microspheres and other pharmaceutical dosage forms 2,3

The primary role of NAC is associated with its antioxidant and anti-inflammatory activity, which favors the maintenance of a cellular redox imbalance