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As a pro-inflammatory steroid hormone, HA induces SLCI in the ovaries by stimulating monocyte infiltration, enhancing ROS production, and activating the NF-B pathway, which contributes to metabolic disorders in PCOS patients (141)

5 images per tissue were randomly collected from grey matter at 63X magnification and 2X digital zoom through a Z stack of 10-12 m with optimal spacing (0.27 m) at a resolution of 512 x 512 pixels

This indicates that extended exposure to consecutive NS may accelerate telomere erosion, consistent with the hypothesis that chronic circadian disruption can promote cellular aging 239

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