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The problem with DPL is its minimal BBB permeability and increase in the dose frequency leads to significant cholinergic adverse effects

CrossRef A Plant PhotoregulatorInspired SType Heterojunction System for Diabetic Keratopathy via TriModal LightDriven Immunometabolic Reprogramming, Tissue Repair, and Antibacterial Activity Mengzhen Zhao, Zhibin Zhou, Yuxuan Wei, Xiangfan Huang, Zhiyong Zhou, Jiaheng Chen, Haoxin Cheng, Xiaotian Hu, Xiaolei Wang Advanced Science.2026;[Epub] CrossRef Determinants of COVID-19 and Influenza Vaccination Among People with Diabetes Mellitus in Primary Health Care Mariana Rodrigues Fernandes Alves Lemos, Stela de Azevedo Camtamos, Maria Eduarda Perptuo Vilano, Silmara Nunes Andrade, Michael Jackson Oliveira de Andrade, Camila Fernanda Cunha Brando, Ana Paula Sayuri Sato, Eliete Albano de Azevedo Guimares, Valri Vaccines.2026

The statistical significance was calculated using a one-sided Fishers exact test, evaluating the over-representation of functional gene sets against the null hypothesis of no association, with multiple comparison correction applied using the Benjamini-Hochberg method