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According to a 2013 study published in Neurologic Clinics, common B12 deficiency treatment regimens include 1,000 micrograms of B12 injections daily for 5 to 7 days followed by 1,000 micrograms on a monthly basis, or B12 injections once weekly for four weeks followed by monthly injections

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Metformin works by improving the bodys sensitivity to insulin, thereby reducing blood sugar production in the liver and increasing glucose uptake in the muscles

That's my two pennorth from a retired scientist, not a medic
