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These structures are similar to those found in a wide variety of neurological diseases as axonal defects (and impaired axonal transport) in the form of swellings that accumulate excessive amounts of proteins, organelles, and vesicles [55]

It is because tissue repair is multifactorial

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FAO blue staining also revealed that MLN4924 inhibited FAO in TECs, as quantified by fluorescence intensity (Figs
