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These alterations in levels have likely taken years to manifest resulting in well-established functional deficits
Physiologically, this lowering of GSH led to increased LDH release ( P = 0.031), consistent with redox activation of ferroptosis and cell death (Figure 4C and refs
In presenting these findings, the article highlights the therapeutic potential of targeting Nrf2 pathways to improve metabolic health and treat metabolic disorders
The arteries were then isolated from the sacrificed mice and imaged using the IVIS imaging system to visualize the distribution of the NPs
