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To date, riluzolea glutamate-modulating drug with anti-excitotoxic effectsremains the only therapy shown to slow ALS progression and prolong survival by roughly 23 months ( 2+ overload, leading to mitochondrial damage and production of Reactive Oxygen Species (ROS) (Williams et al., 1997

The peptides most studied in this space each address at least one of these constraints

explored the direct intradiscal injection of antibodies against NGF or NGF receptors (trkA and p75 NTR ) to suppress downstream CGRP neurotransmitter expression in projecting DRGs

After 30 days, even refrigerated peptides begin losing potency measurably