5-amino-1mq nnmt inhibition mechanism — Inhibition, NAD+ Preservation & Adipose Tissue Metabolic Reprogramming Nicotinamide N-Methyltransferase in Cardiovascular Diseases:
Description
Moret E

On day 9 post-differentiation, cells were subjected to quantitative oil red O (Thermo Fisher Scientific

5-Amino-1MQ (5-amino-1-methylquinolinium) is the most studied inhibitor of nicotinamide N-methyltransferase (NNMT) an enzyme that acts as a metabolic brake in fat cells by depleting both SAM (S-adenosylmethionine) and NAD+ precursors

[DOI] [PubMed] [Google Scholar] Loring H
