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In 2015, however, we reported the surprising observation that mice in which all hepatocytes are constitutively TrxR1/Gsr-null are long-term viable and sustain relatively normal hepatic activities [107]

It may be a signal to explore other therapies with a provider

First, only male db/db mice were used, which may not capture sex-dependent metabolic responses, as female mice often exhibit different disease progression and therapeutic sensitivity (73)

Other catechins like EGCG are unstable in alkaline conditions and are not readily absorbed [5]
