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Additionally, choline contributes to the production of lipid mediators such as lysophosphatidylcholine (lysoPC), sphingomyelin, and platelet-activating factor (28)

Given that WD is characterized by high levels of fat, sugar and cholesterol, it is also more likely to contribute to dyslipidemia and atherosclerosis

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As the rate-limiting enzyme, -BBD shows predominant expression in hepatic, renal, and cerebral tissues (14)
