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Such harmonization is essential to enable meaningful cross-study comparisons, identify the most hazardous particle profiles, and ultimately inform science-based regulatory thresholds and safety guidelines

We found that NOX1 inhibited the expression of Nrf2/HO-1, but the activation of Nrf2 improved the oxidative damage to chondrocytes in vivo and vitro

Nature 463 , 899905 (2010)
