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A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family

Since no homozygous variants have been found, we selected the lines that have one allele with the target mutation and the other with large deletion (SOD1-D91A) or premature termination codon (SOD1-G128R) to maximize potential damage and make the pathological phenotype more perceptible (Fig

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