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Levels in the low-normal range, between 200 and 300, may warrant supplementation even without overt symptoms, particularly in patients with risk factors for deficiency

In the high dosage subgroup (above 0.5 g/kg/day), the mortality rate in the glutamine group was significantly higher than that of the control group (33.5% versus 28.2%

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It is also deliberately produced by immune cells through NADPH oxidase as part of the respiratory burst used to eliminate pathogens