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TLR4, MyD88, and IRAK4 form a complex called the middosome, that acts as a platform to recruit other members of the IRAK family, such as IRAK1 and IRAK2
Small hernias can be asymptomatic or have varying degrees of symptoms, including pain or discomfort as the hernia contents protrude through the defect

A mother microtubule with splayed or spread protofilaments emerging into new daughter microtubules was identified, which presumably represented an intermediate in the microtubule assembly process (Fig

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