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ZhuXLuRZhangGFanLZhanYChenGet alDiallyl trisulfide attenuates alcohol-induced hepatocyte pyroptosis via elevation of hydrogen sulfide

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Conclusions Some defects in CoQ biosynthesis induce an increase in life span in animal models, most likely due to either a mild reduction in the flow of electrons in the mitochondrial respiratory chain and the subsequent decrease in ROS production or early mitochondrial dysfunction and physiological adaptation to this conditionthe latter phenomenon being compatible with the concept of mitohormesis

Nearly all the stabilisation effect was observed at a GSH concentration of 1 mM, suggesting that this might be a practicable additive for vaccine formulation