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doi: 10.1080/17425247.2022.2081320

It binds poorly to IGF-binding proteins, which normally sequester IGF-1 in the body, allowing it to remain active and available for a significantly longer period

Our Take Three months into your training block, that tub of creatine powder sitting in your bag has already converted a meaningful chunk of its active creatine into creatinine, a waste byproduct your body simply excretes

Animal studies show LR3 IGF-1 increases body weight gain, nitrogen retention, and food conversion efficiency (Tomas et al., 1993) and suppresses muscle protein degradation pathways within an hour (Sacheck et al., 2004)