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PANs can be activated by mechanical and chemical signals, and thus transfer information on the status and content of the gut to the nervous (enteric and central), immune, and hormone system, allowing the integration of signals to promote gut and whole-body homeostasis (Rhee et al., 2009

[DOI] [PubMed] [Google Scholar] 108.Kucuktulu E., Guner A., Kahraman I., Topbas M., Kucuktulu U

Kwon, Y.-C

109, 739749.10.1161/CIRCRESAHA.111.245530 96 PhelanD.WinterG
