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5-Amino-1MQ's mechanism centers on NNMT inhibition: NNMT inhibition : Selectively blocks NNMT with an IC50 of approximately 1.2 microM
This choice was primarily influenced by the main characteristics of CD38, which were initially identified at an early Cluster of Differentiation (CD) Workshop as a T-cell activation antigen
That is intentional: the two vial sizes reflect two different documented protocols and two different concentration setups, and it is a reminder never to eyeball a dose across vial sizes
