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Description
A number of underlying mechanisms have been proposed, including increased oxidative stress, disruption of normal hormonal and neurological signaling, impaired cellular and mitochondrial processes, formation of abnormal proteins, and DNA damage

D.et al (2018a)

Most importantly, protection of serum-deprived cells by GSB-106 also engages TrkB/Akt-dependent inactivation of pro-apoptotic BAD protein and suppression of caspases-9 and 3/7

Cell Death Dis (2018) 9(7):738
