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Description
Chambers, J
Niekerk LA, Gokul A, Basson G, Badiwe M, Nkomo M, Klein A, Keyster M
5 In -thalassemia, the release of increased amounts of erythroferrone by the expanded erythroid marrow suppresses hepcidin secretion, thus increasing iron absorption from the gut and iron release by reticuloendothelial cells and leading, in turn, to parenchymal iron overload, even in the absence of RBC transfusion
This approach helps in identifying the most significant factors and their interactions [92]
