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Research doses in studies range from 600 mg to 1,200 mg twice daily, but this remains investigational and should only be used under medical supervision

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Dong Y, Yang Q, Jia S, Qiao C (2007) Effects of high pressure on the accumulation of trehalose and glutathione in the Saccharomyces cerevisiae cells
Murine model investigations have revealed that probiotics can adapt to host physiological stresses, potentially contributing to the development of antibiotic resistance (555)
