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In contrast, HDAC9 overexpression rescued this deficit, normalizing the discrimination index (Fig

In addition to its impact on the skin, plaque psoriasis can extend its influence on the joints, leading to a potentially debilitating form of arthritis causing pain and reduced mobility

Whereas LOX and LOXL1 both require proteolytic cleavage for activation, LOXL2-4 are active in both processed and non-processed forms (Rodriguez et al ., 2010

In a double-blinded, placebo trial in elderly subjects, Bao et al