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A cohort study found that the intake of total fat, monounsaturated fatty acids, and polyunsaturated fatty acids was significantly associated with a lower risk of PD, however, no association was found between dietary saturated fat, cholesterol, or trans-fat and PD (104)

CSE has been found predominantly in the liver, kidney, thoracic aorta, ileum, portal vein, uterus, pancreatic islets and in the placenta

Activation of the TGF- signaling cascade in VSMCs increases GRK2 expression, consequently inhibiting Ang II-induced VSMC proliferation and migration [139]

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