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Morphine as a potential oxidative stress-causing agent

doi: 10.3390/metabo12040296

The vitamin is a cofactor for methionine synthase, which catalyzes the conversion of homocysteine to methioninerequired for the formation of S-adenosylmethionine, a universal methyl donor for almost 100 substrates, including DNA, RNA, hormones, proteins, and lipids

otherwise dipeptide is converted to glutamate by GCT and oxoprolinase.[25] Glutathione functions in systemic health Glutathione has been considered as a true protagonist in cellular regulation.[112] Interrelations linking the antitoxic, AO, prooxidant, and modulator roles of glutathione in cellular homeostasis have been outlined by Pompella et al ., in 2003.[112] Glutathione is involved in the formation and maintenance of protein disulfide bonds, as well as in the amino acids transport across cell membranes