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Description
Sobrino-Plata et al., 2009) Cd was observed as a major PC-inducer
Briefly, dextran sulfate sodium (DSS) (MP biomedicals, #160110) was administered to C57BL6 mice (36 months old) for 5 days
PMC 10619894
PK drug scientists in early discovery are often asked if efficacy is Cmax or AUC driven following early preclinical pharmacology assessments this question is less about PK and relates more to the test articles affinity and reversibility with the molecular disease target
