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Description
Characterization of an ultra-violet inducible gene that encodes glutathione S-transferase in Arabidopsis thaliana

Moreover, PHGDH upregulation confers resistance to MEK inhibitors in NRAS-mutant melanoma, whereas targeted PHGDH inhibition restores the sensitivity of resistant tumors to MAPK signaling pathway inhibitors by reducing intracellular glutathione levels and enhancing oxidative stress (89, 90)

FEBS Lett 538:1418

Rat livers were placed in Thermo-ROS solution containing 10% dimethyl sulfoxide (DMSO), and stored at -20 0 C for three days (72 hours)
