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Although qPCR data indicate that RNAi reduces gene expression by over 80% in pdr-1 and pink-1 (RNAi) conditions (Supplementary Figure S5) seemingly parallel regulation of neurodegeneration observed in pdr-1 (RNAi), and UPS-metabolite toxicity conditions may be due to hypomorphic addition of stressors

In research settings, it is utilized to investigate downstream signaling activity associated with cellular development, structural integrity markers, and tissue-level growth dynamics

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This dynamic regulation indicated a potential role for SLC25A40 in macrophage activation during inflammatory conditions