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glutathione an antioxidant Participation in the Prevention of Cardiovascular Diseases Glutathione: Antioxidant Properties Dedicated to
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In rat pinealocytes (the melatonin-producing cells of the pineal gland), Epitalon was shown to upregulate both AANAT (arylalkylamine N-acetyltransferase, the rate-limiting enzyme in melatonin production) and pCREB (a transcription factor involved in melatonin gene expression)
A toxic dose has never been recorded
In contrast, GSH-dependent proteins like glutaredoxin (GRx) and GST were transcriptionally upregulated in these mutants [115]
