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[DOI] [PubMed] [Google Scholar] Kucukgoncu S

Vitamin B 12 Testing in People With Suspected Vitamin B 12 Deficiency

The deficiency of B-vitamins may impair the homocysteine-methionine cycle 23 , which in turn can lead to reduced glutathione levels

While current treatments focus on symptomatic, palliative, and preventive patient care, future therapeutics should focus on replacement, repair, or compensation of the nonfunctional and/or deficient enzyme through hepatic delivery of the gene or protein