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AChE enzyme A 0.4 mL portion of the homogenate is introduced into a cuvette containing 2.6 mL phosphate buffer solution (0.1 M, pH 8) and 100 L of DTNB

10.1016/j.cellsig.2012.01.008 215 ReczekC.ChandelN

Additionally, mRNA expression of iron response element binding protein 2, encodes a master regulator of iron metabolism), and CS (citrate synthase, regulating the mitochondrial fatty acid metabolism) was upregulated in both models, while ACSF2 ((acyl-CoA synthetase family member 2, regulating the mitochondrial fatty acid metabolism) was upregulated only in APPswe/PS1dE9 mice

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