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The goal is to create a more conducive environment for restorative sleep, which in turn reduces daytime fatigue, enhances mental clarity, and improves overall well-being

The first clue that DNA methylation was relevant to aging came from a study by Steve Horvath, who showed that if you look at where those chemicals are added on our genome it actually is quite predictable for age, and I could take some of your DNA, take it back to my lab and predict when youre going to die based on which genes have these methyl addition or subtraction

Behav Pharmacol 2008;19:747-50

They were then intracardially perfused with saline, followed by 4% paraformaldehyde in 0.1 M phosphate-buffered saline (PBS, pH 7.2), at the final phasefollowing terminal physiological and behavioral assessments