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Redox proteomics indicate that SS-31 reverses oxidative modifications of focal adhesion molecules near the plasma membrane and myelin sheath proteins surrounding motor neurons, suggesting that mitochondrial redox biology influences cellular structures far beyond the mitochondria themselves

There was no difference between the two arms in the incidence of non-hematological or severe hematological toxicity

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The present study observed that the expression of pSTAT3Ser727, pSTAT3Tyr705, p65 (both in the cell nucleus and whole-cell), collagen I, MMP-1 and MMP-13 were reduced, while the levels of IB were increased by administration of prednisone, ibuprofen and betamethasone