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Description
The headache phase follows the prodromal or aura stages of a migraine, marked by the activation and sensitization of the trigeminovascular system (TVS) and brainstem, leading to disrupted sensory processing and various neurological symptoms indicative of altered brain excitability (29)
Considering the clinical differences between early-onset Alzheimers disease (EOAD) and LOAD, future investigations should explore how these compounds interact with subtype-specific pathological processes

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