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USP preparation created for multi-dose use by adding a bacteriostatic preservative to sterile water for injection

[DOI] [PubMed] [Google Scholar] [130].Martini F, Rosa SG, Klann IP, Fulco BCW, Carvalho FB, Rahmeier FL, Fernandes MC, Nogueira CW, A multifunctional compound ebselen reverses memory impairment, apoptosis and oxidative stress in a mouse model of sporadic Alzheimers disease

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When injected subcutaneously, this charge temporarily disrupts the pH balance of the surrounding tissue, triggering a brief localised inflammatory response