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[PubMed: 17141625] 443

Foam or bubbles

Large-scale clinical studies in humans are still required to confirm their safety, efficacy, and potential therapeutic value

At week 16, patients who did not meet the American College of Rheumatology criteria for 20% improvement (ACR20) were switched from 15mg of oral MTX to 15mg of SC MTX and from 15mg of SC MTX to 20mg of SC MTX for the remaining 8 weeks, still in a blinded manner
