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This increased BMD of 0.16 g/cm 2 of the lumbar spine, represented a 15.9% improvement

Nevertheless, many investigators have quantified N-acetylneuraminic acid (sialic acid) per young and per old RBC and then claimed that sialic acid decreased with cell age and the exposed remainder may act as a senescent cell marker, capable to trigger/mediate their selective removal (Gutowski et al., 1991