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Its made of chondrocytes , cells that create a strong matrix of collagen , proteoglycans , and glycoproteins

Glyoxalases, the key enzymes in the detoxification of methylglyoxal, a byproduct of glycolysis and precursor of advanced glycation end-products, are compromised by oxidation and downregulation
Guo, J., et al

In future basic and clinical research, can we select appropriate therapeutic drugs for patients with central nervous system diseases based on their susceptibility to disulfidptosis